Search results for "Dipicolinic acid"
showing 2 items of 2 documents
Copper(II)-dipicolinate-mediated clickable azide–alkyne cycloaddition in water as solvent
2018
Copper(II)-dipicolinate complex [CuIIL(H2O)2] (1) (H2L = dipicolinic acid (H2dipic)) was synthesized via oxidation of copper(I) iodide and pyridine-2,6-dicarboxylic acid in water and acetonitrile in the presence of glycine. Complex 1 was characterized by FT-IR and elemental analysis and its structure confirmed by single crystal X-ray analysis. This complex is an efficient precatalyst that mediates azide-alkyne cycloaddition reactions in water at room temperature either in the absence or presence of a reducing agent. Compound 1-mediated azide-alkyne cycloaddition affords alkyl/aryl substituted 1,2,3-triazole heterocycles in a regioselective manner and excellent yields under very mild reactio…
UV resistance of Bacillus subtilis spores - Involvement of DPA and characterization by photonic microscopy
2022
The aim of this project was to study the UVc resistance of Bacillus subtilis spores. The first part of this project focused on the dipicolinic acid molecule (DPA) which is known to be involved in the UV resistance of spores. However, some points remain unresolved. In particular, it is known that this molecule forms fluorescent photoproducts (DPAp), which were not identified at the beginning of this project. No information concerning the role of these DPAp in UVC resistance was available at that time. During this project, a protocol was established to follow the appearance of these photoproducts directly inside the spore core. A method was also set up to artificially introduce DPAp into the …